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Significats de cholesteryl ester en anglès
portuguès
éster do colesteril An ester of cholesterol.
Termes relacionats
Sinònims
Examples for "cholesteryl esters"
Examples for "cholesteryl esters"
1
However, implication of LXRs in the selective uptake of cholesteryl esters from lipoproteins in human macrophages has never been reported.
2
A simple method has been developed for labelling human plasma lipoproteins to high specific radioactivity with radioactive cholesteryl esters in vitro.
3
They serve to transport endogenously synthesized lipids, mainly triglycerides (but also some cholesterol and cholesteryl esters) to peripheral tissues.
4
Lysosomal acid lipase (LAL) is a key enzyme that cleaves cholesteryl esters and triglycerides to generate free fatty acids and cholesterol in lysosomes.
5
Inhibition of ACAT, the enzyme which catalyses the intracellular formation of cholesteryl esters, is a very attractive target for the treatment of hypercholesterolaemia and atherosclerosis.
1
This occurs through the maintenance of caveolae cholesterol content by cholesterol ester uptake from HDL.
2
Cholesteryl ester transfer protein is a plasma glycoprotein that transfers cholesterol ester between lipoprotein particles.
3
Conclusions: The authors concluded that FEL irradiation can remove cholesterol ester selectively from human atheromatous CA plaques.
4
In the absence of active LPL in the same tissue, inactive LPL only mediates selective cholesterol ester uptake.
5
We observed abnormal hepatic accumulation of cholesterol in the homozygote individuals, supporting the diagnosis of cholesterol ester storage disease.
1
The process begins with a vascular injury that is complicated by the deposition of cholesterol esters and cholesterol.
2
Increases in absolute amounts of EPA and DHA in fasting serum triglycerides, cholesterol esters and phospholipids were examined.
3
On the other hand, an EPA-rich diet produced a marked increase of this fatty acid, especially in cholesterol esters.
4
In contrast, the incorporation of exogenous oleate into secreted triacylglycerols and cholesterol esters was unaffected by deficiency of ABHD5.
5
The cholesterol ester transfer protein (CETP) facilitates the transfer of HDL cholesterol esters from plasma to the liver.
Ús de cholesteryl ester en anglès
1
The mechanism of cholesteryl ester accumulation in smooth muscle cells was investigated.
2
When membrane cholesterol levels are low, absorption of cholesterol effectively drives cholesteryl ester hydrolysis.
3
This difference is consistent with reports of the nonendocytotic selective uptake of HDL-associated cholesteryl ester.
4
Unexpectedly, cholesteryl ester transfer protein was not required to determine the human-like cholesterol lipoprotein profile.
5
Our results demonstrate that lysosomal hydrolysis of cholesteryl ester is independent of the presence of extracellular acceptors.
6
We show that net hydrolysis of cholesteryl ester is coupled to the transfer of cholesterol to membranes.
7
These results show that aortic smooth muscle cells in cooperation with macrophages can accumulate cholesteryl ester from beta-VLDL.
8
In endosomes and lysosomes cholesteryl ester is hydrolyzed by acidic cholesteryl ester hydrolase producing cholesterol and fatty acids.
9
Here, we have studied endosomal and lysosomal cholesteryl ester metabolism in cultured mouse macrophages and with cell-free extracts.
10
J774 and elicited mouse peritoneal macrophages were loaded with cholesteryl ester within lysosomes through phagocytosis of sonicated lipid droplets.
11
Human plasma lipid transfer protein ( cholesteryl ester transfer protein) has been characterized for its solution and surface properties.
12
The formation of cholesterol monohydrate crystals was observed in cholesteryl ester-loaded macrophages after a 48-h incubation by polarizing light microscopy.
13
A reduction in cholesteryl ester transfer protein (CETP) activity has been advanced to explain most lipid-modulating effects of NA.
14
Additional Mendelian randomization analysis failed to clarify the involvement of cholesteryl ester transfer protein in alcohol-related changes in lipoprotein cholesterol levels.
15
Electron microscopy and acid phosphatase cytochemistry of lysosomes in cholesteryl ester-loaded cells confirmed that cholesterol crystal formation occurred within lipid-loaded lysosomes.
16
Thus, the present data do not rule out the involvement of direct HDL-cell interaction in the selective uptake of HDL cholesteryl ester.